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…showed last 75 words of 729 total…Union. The most important general factor that led the United States into civil war was the issue of slavery. Though the causes of the war involved many different elements such as conflicting nationalisms, the definition of freedom, and the preservation of the Union; a large number of them dealt with slavery. The issue of slavery generated very strong feelings in the North and South and events like those described in this essay escalated the tension.