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…showed last 75 words of 1024 total…use of creatine may be much worse than the short-term adverse effects. Clinical Pharmacology (Interactions) reports that one case report shows that a healthy twenty-five year old taking cyclosporine, an immune system drug used to help transplants turn out successful, began use of creatine and soon experienced kidney dysfunction. These possible adverse effects of creatine use should be more widely publicized so parents and teenagers can know the dangers they face in using the supplement.