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…showed last 75 words of 962 total…particularly during the initial months of therapy and if the dose of either drug is increased. Your doctor may also monitor the level of certain muscle enzymes in your body, but there is no assurance that such monitoring will prevent the occurrence of severe muscle disease. ZOCOR is less effective in patients with the rare disorder known as homozygous familial hypercholesterolemia. Pediatric Use: ZOCOR is not recommended for children or patients under 20 years of age.